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    Drinking more than two alcoholic drinks daily in middle-age may raise your stroke(中风) risk more than traditional factors such as high blood pressure and diabetes（糖尿病）, according to new research in the American Heart Association journal Stroke.

    In a study of 11,644 middle-aged Swedish twins who were followed for 43 years, researchers compared the effects of an average of more than two drinks daily ("heavy drinking") to less than half a drink daily ("light drinking").

The study showed that:

·Heavy drinkers had about a 34 percent higher risk of stroke compared to light drinkers.

·Mid-life heavy drinkers (in their 50s and 60s) were likely to have a stroke five years earlier in life irrespective of genetic and early-life factors.

·Heavy drinkers had increased stroke risk in their mid-life compared to well-known risk factors like high blood pressure and diabetes.

·At around age 75, blood pressure and diabetes appeared to take over as one of the main influences on having a stroke.

    Past studies have shown that alcohol affects stroke risk, but this is the first study to pinpoint differences with age. "We now have a clearer picture about these risk factors----how they change with age and how the influence of drinking alcohol shifts as we get older," said Pavla Kadlecová, M.Sc., a statistician at St. Anne's University Hospital's International Clinical Research Center in the Czech Republic.

    Researchers analyzed results from the Swedish Twin Registry of same-sex twins who answered questionnaires in 1967-1970. All twins were under age 60 at the start. By 2010, the Registry had provided 43 years of follow-up, including hospital discharge(出院) and cause of death data.

    Researchers then sorted(整理) the data based on strokes, high blood pressure, diabetes and other cardiovascular (心血管)incidents. Almost 30 percent of participants had a stroke. They were categorized(将……分类) as light, moderate, heavy or non-drinkers based on the questionnaires. Researchers compared the risk from drinking and health risks like high blood pressure, diabetes and smoking. Among identical twin pairs, siblings(兄弟姐妹) who had a stroke drank more than their siblings who hadn't had a stroke, suggesting that mid-life drinking raises stroke risks regardless of genetics and early lifestyle.

    The study is consistent (一致)with the American Heart Association's recommended limit of two drinks a day for men and one for women. That's about 8 ounces of wine for a man and 4 ounces for a woman.

    Regular heavy drinking of any kind of alcohol can raise blood pressure and cause heart failure or irregular heartbeats over time, in addition to stroke and other risks. "For mid-aged adults, avoiding more than two drinks a day could be a way to prevent stroke in later productive age ," Kadlecová said.