第二部分：英语知识运用（共两节,满分45分）
第一节 单项填空(共15小题；每小题1分，满分15分)
从A、B、C、D四个选项中，选出可以填入空白处的最佳选项，并在答题卡上将该项涂黑。
---It is reported that there is____ big breakthrough in the cancer treatment.
---If only my son could be brought back to ____ life!
A.a; / B./; a C.the;the D.a;the

We are very annoyed ______ his mistake, because we have emphasized this for several times.   

A．at/about

B．with

C．on

D．to